18 年前
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美丽聪慧的桧山冬实（仲间由纪惠 饰），是圣卡洛琳娜综合医院脑外科的主治医生，她拥有高超的医术，尤其是针对脑外科疑难之症病毒动脉轮闭塞症，拥有一套独特的对治方法。某天，不幸罹患这一病症的少女伊原沙耶香前来求助。为了治好女孩，为医院创出名气，院方为桧山配备了最精良的手术团队。介绍沙耶香来医院的医疗协调员中原永远子（濑户朝香 饰）虽然因过往种种而对桧山心存芥蒂，但面对这名脑外科专家精湛的技艺仍不得不表示敬佩。可未过多久，沙耶香病情突然恶化，最终撒手人寰。为了查出原因，桧山打算调取手术录像，却发现录像DVD失窃，硬盘数据被删除。似乎有人在暗中摧毁关于桧山以及圣卡洛琳娜医院的一切……
本片根据秦建日子的原作改编。。After the divorce, Lisa was left with two children. Soon she meets a woman who is called her relative and says that their family has a family curse and that Lisa's boys are in mortal danger. Lisa refuses to believe in superstitious fears, but later strange visions begin to visit her, and she realizes that the curse turns out to be real. Now she must save her children from evil ...。
